simvastatin(Zocor)

HMG-CoA reductase inhibitor (statin)

Pronunciation

/sɪmvəˈstætɪn/

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At a glance

Generic name: simvastatin
Brand names: Zocor
Therapeutic class: HMG-CoA reductase inhibitor (statin)
Mechanism (summary):

Clinical pearls

Take in the evening for best LDL reduction (cholesterol synthesis peaks at night).
Report unexplained muscle pain, tenderness, or dark urine.
Avoid grapefruit juice.
Pregnancy category X - use contraception.
### NAPLEX practice notes

Related drugs in this class

atorvastatin

Lipitor

rosuvastatin

Crestor, Ezallor Sprinkle

pravastatin

Pravachol

Sources

See how simvastatin appears in NAPLEX-style questions

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