trazodone(Desyrel, Oleptro)
Serotonin antagonist and reuptake inhibitor (SARI)
Pronunciation
/ˈtræzəˌdoʊn/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- trazodone
- Brand names
- Desyrel, Oleptro
- Therapeutic class
- Serotonin antagonist and reuptake inhibitor (SARI)
- Mechanism (summary)
- <!-- AI-DRAFTED: 2026-06-23 -->
Clinical pearls
- Take with food to reduce nausea and improve absorption.
- Bedtime dosing reduces daytime drowsiness.
- Rise slowly - significant orthostasis.
- Men: seek emergency care for any painful, prolonged erection.
- Avoid alcohol and CNS depressants.
Sources
See how trazodone appears in NAPLEX-style questions
PharmDHub Premium includes a full drug card, dosing, boxed warnings, drug-drug interactions, and practice questions built around this drug.