tamoxifen(Nolvadex, Soltamox)
Selective estrogen receptor modulator (SERM)
Pronunciation
/təˈmɒksɪfɛn/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- tamoxifen
- Brand names
- Nolvadex, Soltamox
- Therapeutic class
- Selective estrogen receptor modulator (SERM)
- Mechanism (summary)
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Clinical pearls
- Take once daily, same time each day.
- Report unusual vaginal bleeding promptly - need workup for endometrial cancer.
- Report leg swelling/pain or sudden vision changes.
- Avoid SSRIs that strongly inhibit CYP2D6 (paroxetine, fluoxetine) - use venlafaxine instead.
- Use non-hormonal contraception; teratogenic.
Related drugs in this class
Sources
See how tamoxifen appears in NAPLEX-style questions
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