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sertraline
Pronunciation
/ˈsɜːrtrəliːn/ Mechanism of action Selectively inhibits the presynaptic serotonin transporter (SERT), increasing serotonin availability in the synaptic cleft. Has weak effects on dopamine reuptake and minimal effect on norepinephrine. Therapeutic effect on depression and anxiety emerges over 2--6 weeks, likely via downstream receptor adaptation and neuroplasticity changes \\[1\\]. Standard dosing -/
International Phonetic Alphabet (IPA).
At a Glance
Generic name: sertraline
Brand names: Zoloft
Therapeutic class: Selective serotonin reuptake inhibitor (SSRI)
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