sacubitril/valsartan(Entresto)
Angiotensin receptor-neprilysin inhibitor (ARNI)
Pronunciation
/səˈkjuːbɪtrɪl/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- sacubitril/valsartan
- Brand names
- Entresto
- Therapeutic class
- Angiotensin receptor-neprilysin inhibitor (ARNI)
- Mechanism (summary)
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Clinical pearls
- Take twice daily; can take with or without food.
- DO NOT use within 36 hours of an ACE inhibitor (angioedema risk).
- Monitor BP, potassium, and kidney function.
- Report swelling of face/tongue/lips, severe dizziness, or fainting.
- Pregnancy category D - effective contraception required.
Sources
See how sacubitril/valsartan appears in NAPLEX-style questions
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