mepolizumab(Nucala)
Anti-IL-5 monoclonal antibody
Pronunciation
/mɛpoʊˈlɪzʊmæb/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- mepolizumab
- Brand names
- Nucala
- Therapeutic class
- Anti-IL-5 monoclonal antibody
- Mechanism (summary)
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Clinical pearls
- Self-administered SC (auto-injector or syringe) after training.
- Rotate injection sites (upper arm, thigh, abdomen).
- Consider zoster vaccine before starting.
- Do not stop inhaled corticosteroids abruptly.
- Used as ADD-ON for severe eosinophilic asthma (blood eos >=150-300 cells/uL).
Sources
See how mepolizumab appears in NAPLEX-style questions
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