imatinib(Gleevec)
BCR-ABL tyrosine kinase inhibitor (TKI)
Pronunciation
/ɪˈmætɪnɪb/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- imatinib
- Brand names
- Gleevec
- Therapeutic class
- BCR-ABL tyrosine kinase inhibitor (TKI)
- Mechanism (summary)
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Clinical pearls
- Take with food and a large glass of water to reduce GI upset.
- Report swelling, weight gain, shortness of breath, or severe muscle cramps.
- Avoid grapefruit juice.
- Lifetime therapy in most CML patients; do not stop without consulting oncology.
- Adherence is critical for sustained molecular response.
Sources
See how imatinib appears in NAPLEX-style questions
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