bupropion(Wellbutrin, Wellbutrin SR, Wellbutrin XL)
Norepinephrine-dopamine reuptake inhibitor (NDRI); aminoketone antidepressant
Pronunciation
/bjuːˈproʊpiɒn/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- bupropion
- Brand names
- Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban, Aplenzin, Forfivo XL
- Therapeutic class
- Norepinephrine-dopamine reuptake inhibitor (NDRI); aminoketone antidepressant
- Mechanism (summary)
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Clinical pearls
- Take in the morning to reduce insomnia.
- Swallow XL/SR whole.
- Allow several weeks for antidepressant effect.
- Do not stop abruptly if used for depression.
- Effective for depression and smoking cessation; no sexual side effects or weight gain.
Sources
See how bupropion appears in NAPLEX-style questions
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